The Samuel Waxman Cancer Research Foundation

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William A. Weiss, M.D., Ph.D.

Institutional Affiliation:
Professor of Neurology, Pediatrics, and Neurosurgery
University of California, San Francisco
http://waweisslab.ucsf.edu/
http://bps.ucsf.edu/pspg/faculty/pages/weiss.html

Education
Tufts University, B.S.
Stanford University, M.D., Ph.D.

Internship
Children’s Hospital Boston

Residency
Children’s Hospital Boston (Pediatrics) and University of California, San Francisco (Neurology/Child Neurology)

Research
Developmental Therapeutics in Neuroblastoma and Glioma

Impact
Innovative therapies and combination therapies for these cancers.

Summary of Research
Our laboratory is broadly interested in developing and characterizing mouse models that faithfully recapitulate the biology and genetics of human tumors of the nervous system, and using observations in the mouse to inform the biology, genetics, and therapy of human tumors. Specifically we are:

  1. Identifying the subsequent genetic events that promote tumorigenesis.
  2. Studying cancer stem and progenitor cells to understand their contribution to malignant progression.
  3. Evaluating new targets, therapies, and mechanistic rationales for combining targeted agents.
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