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Tumor Dormancy Research
Amongst this program’s major accomplishments is the development of a human cancer model useful to discover a single but key protein on the surface of cancer cells. This protein can make a cancer cell dormant and less aggressive. Specific inhibitors of this protein have been designed to maintain this cancer dormancy. These inhibitors are being refined using structural biology methods. It is anticipated that preclinical development including collaboration with pharmaceutical companies will result in drugs that will be tested in clinical trials to drive cancer cells to become dormant. This would represent a groundbreaking advance as it would help convert cancer into a chronic disease.
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