Microorganisms in Your Gut Could Help Prevent and Treat Colorectal Cancer

New Study Highlights Role of a Healthy Diet in Decreasing Risk

New York, NY – May 1, 2023 - A recent study sheds new light on the development and treatment of colorectal cancer (CRC). The research, titled "Development and treatment of colorectal cancer: Insights from multi-kingdom microbiota," explores the role of microorganisms (bacteria, viruses, fungi, etc.) that live in our gut in preventing or increasing the risk of developing colon or rectal cancer.

The study published in the April edition of Aging and Cancer, by Wiley Publications in partnership with the Samuel Waxman Cancer Research Foundation (SWCRF), found that changes in the microbiota can lead to inflammation and damage to the gut lining, which could eventually lead to cancer. However, researchers also point out that targeting the microbiota may lead to the development of novel medications to prevent and/or treat colorectal cancer.

Furthermore, researchers highlight that diet plays a vital role in regulating gut microbiota. In fact, study authors point to a meta-analysis which showed how a healthy diet – one including fruits and vegetables, whole grains, nuts and legumes, fish and other seafood, milk, and other dairy products, lowered the risk of CRC incidence. In contrast, a diet characterized by a high intake of red meat, processed meat, sugary beverages, refined sugars, and potatoes was associated with a higher risk.

“While colorectal cancer can occur in young adults, the risk increases as people age with the average age of diagnoses around 68 for men and 72 for women,” said Dr. Samuel Waxman, SWCRF CEO and founder. “This study has important implications for public health due to an increasing older population. I applaud the authors’ clever investigation of microorganism interactions, which will pave the way to manipulate them more accurately in the prevention and treatment of CRC.”

In 2023, an estimated 153,000 adults in the United States will be diagnosed with CRC. Worldwide, CRC is the third most diagnosed cancer and the second leading cause of cancer death. However, colorectal cancer can often be successfully treated when found early. 

Study: Development and treatment of colorectal cancer: Insights from multi-kingdom microbiota

Media Contact:

Wylie Tene

Samuel Waxman Cancer Research Foundation

Director of Marketing and Communications

212-867-4502 / [email protected]